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Age at the time of the relapse in years
Date of disease onset
Date of the relapse
Last EDSS before the relapse
Choose
0.0: Normal Neurological Exam
1.0: No disability, minimal signs in 1 functionnal score
1.5: No disability, minimal signs in more than 1 functionnal score
2.0: Minimal disability in 1 functionnal score
2.5: Mild disability in 1 or Minimal disability in 2 functionnal score
3.0: Moderate disability in 1 functionnal score or mild disability in 3 - 4 functionnal score, though fully ambulatory
3.5: Fully ambulatory but with moderate disability in 1 functionnal score and mild disability in 1 or 2 functionnal score; or moderate disability in 2 functionnal score; or mild disability in 5 functionnal score
4.0: Fully ambulatory without aid, up and about 12hrs a day despite relatively severe disability. Able to walk without aid 500 meters
4.5: Fully ambulatory without aid, up and about much of day, able to work a full day, may otherwise have some limitations of full activity or require minimal assistance. Relatively severe disability. Able to walk without aid 300 meters
5.0: Ambulatory without aid for about 200 meters. Disability impairs full daily activities
5.5: Ambulatory for 100 meters, disability precludes full daily activities
6.0: Intermittent or unilateral constant assistance (cane, crutch or brace) required to walk 100 meters with or without resting
6.5: Constant bilateral support (cane, crutch or braces) required to walk 20 meters without resting
7.0: Unable to walk beyond 5 meters even with aid, essentially restricted to wheelchair, wheels self, transfers alone; active in wheelchair about 12 hours a day
7.5: Unable to take more than a few steps, restricted to wheelchair, may need aid to transfer; wheels self, but may require motorized chair for full day's activities
8.0: Essentially restricted to bed, chair, or wheelchair, but may be out of bed much of day; retains self care functions, generally effective use of arms
8.5: Essentially restricted to bed much of day, some effective use of arms, retains some self care functions
EDSS at the relapse
Choose
1.0: No disability, minimal signs in 1 functionnal score
1.5: No disability, minimal signs in more than 1 functionnal score
2.0: Minimal disability in 1 functionnal score
2.5: Mild disability in 1 or Minimal disability in 2 functionnal score
3.0: Moderate disability in 1 functionnal score or mild disability in 3 - 4 functionnal score, though fully ambulatory
3.5: Fully ambulatory but with moderate disability in 1 functionnal score and mild disability in 1 or 2 functionnal score; or moderate disability in 2 functionnal score; or mild disability in 5 functionnal score
4.0: Fully ambulatory without aid, up and about 12hrs a day despite relatively severe disability. Able to walk without aid 500 meters
4.5: Fully ambulatory without aid, up and about much of day, able to work a full day, may otherwise have some limitations of full activity or require minimal assistance. Relatively severe disability. Able to walk without aid 300 meters
5.0: Ambulatory without aid for about 200 meters. Disability impairs full daily activities
5.5: Ambulatory for 100 meters, disability precludes full daily activities
6.0: Intermittent or unilateral constant assistance (cane, crutch or brace) required to walk 100 meters with or without resting
6.5: Constant bilateral support (cane, crutch or braces) required to walk 20 meters without resting
7.0: Unable to walk beyond 5 meters even with aid, essentially restricted to wheelchair, wheels self, transfers alone; active in wheelchair about 12 hours a day
7.5: Unable to take more than a few steps, restricted to wheelchair, may need aid to transfer; wheels self, but may require motorized chair for full day's activities
8.0: Essentially restricted to bed, chair, or wheelchair, but may be out of bed much of day; retains self care functions, generally effective use of arms
8.5: Essentially restricted to bed much of day, some effective use of arms, retains some self care functions
9.0: Helpless bed patient, can communicate and eat
9.5: Unable to communicate effectively or eat/swallow
Sensory symptoms (only subjectiv signs as paresthesia, dysesthesia, neuropathic pain, etc.)
Choose
Worsening or new symptoms
No change
Proprioceptive ataxia
Choose
Worsening or new symptoms
No change
Lejeune et al. SMILE: a predictive model for Scoring the severity of relapses in MultIple scLErosis
(Journal of Neurology, 2020)